AI-assisted microdissection TESE linked to higher sperm retrieval and live birth rates in azoospermia
Retrospective · Asian J Androl · 2026-11-07. Number 4 in the UrologyWatch Top 5 for November 10, 2026.
In a retrospective cohort of 1,286 men with non-obstructive azoospermia, AI-assisted micro-TESE was associated with higher sperm retrieval rate (68.1% vs 47.6%) than conventional surgery, with improvements also seen in ICSI fertilization, pregnancy, and live birth rates.
Why it matters: Suggests AI-assisted intraoperative guidance during micro-TESE may be associated with improved sperm retrieval, but comparative design and lack of randomization limit causal interpretation.
Limitation: Retrospective, non-randomized comparison across two centers introduces potential selection and surgeon-experience confounding.
Source: Asian J Androl · PubMed 42989887 · DOI 10.4103/aja202644
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