EAU stone risk stratification shows limited accuracy predicting recurrence in large registry analysis
Retrospective · BJU Int · 2026-11-06. Number 2 in the UrologyWatch Top 5 for November 8, 2026.
Using UK Biobank and All of Us data on over 25,000 patients with clinically significant kidney stones, EAU high/low-risk classification predicted 5-year symptomatic recurrence with only modest accuracy (time-dependent AUC 0.61), and decision curve analysis showed no clinical benefit to risk-stratified follow-up.
Why it matters: Is hypothesis generating: raises the question of whether EAU risk stratification criteria need revision, though registry data cannot capture all clinical nuances used in real-world risk assessment.
Limitation: Retrospective registry analysis (UK Biobank, All of Us) relying on diagnostic and procedure codes, which may misclassify risk factors used in the original EAU criteria.
Source: BJU Int · PubMed 42978327 · DOI 10.1111/bju.70525
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