Phase 3 trial compares adjuvant radiotherapy versus observation after cystectomy in MIBC

Phase 3 RCT · MedPage Today · 2026-10-29. Number 4 in the UrologyWatch Top 5 for October 30, 2026.

A multicenter phase 3 randomized trial evaluated adjuvant radiotherapy versus observation following radical cystectomy for muscle-invasive bladder cancer; specific outcome data are not detailed in the available text.

Why it matters: If positive, could inform selective use of adjuvant radiotherapy after cystectomy in high-risk MIBC.

Limitation: Results not reported in the available text; this appears to be a trial report without extractable outcome data here.

Source: MedPage Today · PubMed 42166701 · DOI 10.1200/jco-25-02093

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