T2-MRI radiomics model predicts apical positive margins before prostatectomy

Retrospective · Asian J Androl · 2026-10-22. Number 4 in the UrologyWatch Top 5 for October 22, 2026.

In 235 men with MRI-visible apical prostate tumors, a radiomics model built from T2-weighted MRI predicted apical positive surgical margins with AUC 0.874 in a held-out test set.

Why it matters: Raises the question of whether radiomics could help with preoperative apical margin risk counseling, but needs prospective validation.

Limitation: Single-institution retrospective design with modest sample size and no external validation cohort.

Source: Asian J Androl · PubMed 42902531 · DOI 10.4103/aja202625

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