Frailty does not modify robotic vs open cystectomy outcomes in older adults

Retrospective · Urology · 2026-09-27. Number 2 in the UrologyWatch Top 5 for September 28, 2026.

In a SEER-Medicare emulated trial of 1,750 patients aged 66-89 with bladder cancer, robotic-assisted radical cystectomy showed no significant difference from open surgery in perioperative morbidity or oncologic outcomes, regardless of baseline frailty.

Why it matters: Suggests frailty status alone should not drive the choice between robotic and open cystectomy approaches.

Source: Urology · PubMed 42800544 · DOI 10.1016/j.urology.2026.09.054

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